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Medication Information: Entresto

Brand name: Entresto

Generic name: Sacubitril/Valsartan

What is ENTRESTO?

ENTRESTO is a prescription medicine used to treat adults with long-lasting (chronic) heart failure to help reduce the risk of death and hospitalization. ENTRESTO works better when the heart cannot pump a normal amount of blood to the body.

ENTRESTO may cause serious side effects including:

  • swelling of your face, lips, tongue, and throat (angioedema) that may cause trouble breathing and death. Get emergency medical help right away if you have symptoms of angioedema or trouble breathing. Do not take ENTRESTO again if you have had angioedema while taking ENTRESTO
  • people who are Black or who have had angioedema and take ENTRESTO may have a higher risk of having angioedema
  • low blood pressure (hypotension), which is common, and your risk of low blood pressure is greater if you also take water pills (diuretics). Call your doctor if you become dizzy or lightheaded, or you develop extreme tiredness (fatigue)
  • kidney problems, which are common, and can be serious and can lead to kidney failure
  • increased amount of potassium in your blood (hyperkalemia), which is common

 

The most common side effects also include cough and dizziness.